Article: Developmental synaptic changes increase the range of integrative capabilities of an identified excitatory neocortical connection.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Angulo MC; Staiger JF; Rossier J; Audinat E J. Neurosci., 1999
Connections from 3-week-old rats mean ± SD (n) | Connections from 5-week-old rats mean ± SD (n) | |
---|---|---|
Postnatal days | 17 ± 1 (36) | 33 ± 2 (21) |
Firing Properties1-a | ||
Early accommodation | 15 ± 15% (36) | 12 ± 13% (20) |
Late accommodation | 3 ± 10% (36) | 4 ± 9% (20) |
Spike amplitude (A) | 78 ± 8 mV (36) | 81 ± 5 mV (20) |
Spike duration (t 1/2) | 0.4 ± 0.1 msec (36) | 0.31 ± 0.06 msec (20) |
AHP | −21 ± 3 mV (36) | −25 ± 3.3 mV (20) |
Rin | 0.16 ± 0.06 GΩ (36) | 0.14 ± 0.04 GΩ (20) |
Vrmp | −73 ± 8 mV (34) | −76 ± 3.1 mV (20) |
Unitary EPSCs | ||
Latency | 0.47 ± 0.28 msec (36) | 0.54 ± 0.26 msec (21) |
1st exponential decay (τ1) | 1.3 ± 0.5 msec (22) | 1.3 ± 0.6 msec (15) |
Amplitude of τ1 | 88 ± 12% (22) | 89 ± 7% (15) |
2nd exponential decay (τ2) | 11 ± 6 msec (22) | 17 ± 15 msec (15) |
Amplitude of τ2 | 12 ± 12% (22) | 11 ± 7% (15) |
τ1-b | 1.7 ± 0.5 msec (13) | 1.7 ± 0.4 msec (4) |
NBQX/DNQX Block (−72 mV) | 98 ± 2% (5) | 96.5% and 99.2% (2) |
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
---|---|---|---|---|---|
Neocortex pyramidal cell layer 5-6 | Motor cortex layer 5 glutamatergic excitatory pyramidal neurons synapsing onto motor cortex layer 5 fast-spiking interneurons | spike amplitude (A) | 78.0 ± 8.0 (36) | -- | Data Table |
Neocortex pyramidal cell layer 5-6 | Motor cortex layer 5 glutamatergic excitatory pyramidal neurons synapsing onto motor cortex layer 5 fast-spiking interneurons | spike amplitude (A) | 81.0 ± 5.0 (20) | -- | Data Table |
Neocortex pyramidal cell layer 5-6 | Motor cortex layer 5 glutamatergic excitatory pyramidal neurons synapsing onto motor cortex layer 5 fast-spiking interneurons | spike half-width | 0.4 ± 0.1 (36) | 0.4 (ms) | Data Table |
Neocortex pyramidal cell layer 5-6 | Motor cortex layer 5 glutamatergic excitatory pyramidal neurons synapsing onto motor cortex layer 5 fast-spiking interneurons | spike half-width | 0.31 ± 0.06 (20) | 0.31 (ms) | Data Table |
Neocortex pyramidal cell layer 5-6 | Motor cortex layer 5 glutamatergic excitatory pyramidal neurons synapsing onto motor cortex layer 5 fast-spiking interneurons | AHP amplitude | -21.0 ± 3.0 (36) | 21.0 (mV) | Data Table |
Neocortex pyramidal cell layer 5-6 | Motor cortex layer 5 glutamatergic excitatory pyramidal neurons synapsing onto motor cortex layer 5 fast-spiking interneurons | AHP amplitude | -25.0 ± 3.3 (20) | 25.0 (mV) | Data Table |
Neocortex pyramidal cell layer 5-6 | Motor cortex layer 5 glutamatergic excitatory pyramidal neurons synapsing onto motor cortex layer 5 fast-spiking interneurons | input resistance | 0.16 ± 0.06 (36) | 160.0 (MΩ) | Data Table |
Neocortex pyramidal cell layer 5-6 | Motor cortex layer 5 glutamatergic excitatory pyramidal neurons synapsing onto motor cortex layer 5 fast-spiking interneurons | input resistance | 0.14 ± 0.04 (20) | 140.0 (MΩ) | Data Table |
Neocortex pyramidal cell layer 5-6 | Motor cortex layer 5 glutamatergic excitatory pyramidal neurons synapsing onto motor cortex layer 5 fast-spiking interneurons | resting membrane potential | -73.0 ± 8.0 (34) | -73.0 (mV) | Data Table |
Neocortex pyramidal cell layer 5-6 | Motor cortex layer 5 glutamatergic excitatory pyramidal neurons synapsing onto motor cortex layer 5 fast-spiking interneurons | resting membrane potential | -76.0 ± 3.1 (20) | -76.0 (mV) | Data Table |
Neocortex pyramidal cell layer 5-6 | Motor cortex layer 5 glutamatergic excitatory pyramidal neurons synapsing onto motor cortex layer 5 fast-spiking interneurons | adaptation percent (1 – first/last ISI) | 15.0 ± 15.0 (36) | 15.0 (ratio) | Data Table |
Neocortex pyramidal cell layer 5-6 | Motor cortex layer 5 glutamatergic excitatory pyramidal neurons synapsing onto motor cortex layer 5 fast-spiking interneurons | adaptation percent (1 – first/last ISI) | 12.0 ± 13.0 (20) | 12.0 (ratio) | Data Table |